PRECISION MEDICINE FOR MUSCULOSKELETAL PAIN
Apos® is the technology to stay ahead of the curve.
THE POWER OF APOS®:
A TARGETED INNOVATIVE APPROACH TO ADDRESSING CHRONIC KNEE, HIP AND LOWER BACK PAIN.
By considering each patient’s unique anatomy, biomechanics, neuromuscular responses, and medical history, Apos® delivers personalized treatment tailored to individual needs.
As easy to use as wearing a pair of reading glasses, it results in significant improvements in pain relief, functional ability, and quality of life.
RECOMMENDED BY LEADING GUIDELINES
NICE RECOMMENDS APOS®
National Institute for Health and Care Excellence recommends Apos for patients with knee osteoarthritis (OA) who have tried and failed non-surgical standard care and are candidates for total knee replacement surgery who choose to avoid surgery.
EULAR RECOMMENDS CONSIDERING APOS®
The European Alliance of Associations for Rheumatology (EULAR) Recommends Considering Apos® for Knee and Hip OA.
BACKED BY CLINICAL RESEARCH
JAMA: THE BIOTOK RANDOMIZED CLINICAL TRIAL, EFFECT OF APOS® ON KNEE PAIN IN PEOPLE WITH KNEE OSTEOARTHRITIS
Leading experts in osteoarthritis, including David Felson, MD, MPH, Stephan Reichenbach, MD, MSc, and Peter Jüni, MD, conducted an independent double-blind RCT study
REDUCTION IN PAIN AND IMPROVEMENT IN FUNCTION EXCEEDS THE THRESHOLD FOR CLINICAL SIGNIFICANCE FOR CLINICAL SIGNIFICANCE
%
REPORTED
>30% REDUCTION IN PAIN
%
REPORTED
>50% REDUCTION IN PAIN
%
AVG.
REDUCTION IN PAIN
%
AVG.
IMPROVEMENT IN FUNCTION
As a reference, a different randomized controlled trial (RCT) comparing total knee replacement with non-invasive intervention vs. non-invasive intervention only demonstrated a number needed to treat (NNT) of 7.4 to achieve a 15% reduction in pain.
*Skou S.T. et al. Osteoarthritis and Cartilage, 2018, 26, 1170-1180.
A RECENT STUDY SHOWS 89% OF ELIGIBLE TOTAL KNEE REPLACEMENT PATIENTS AVOID SURGERY FOR UP TO 6 YEARS.
- SUSTAINED PAIN RELIEF: Patients observed a significant reduction in pain and improved function after three months, which was sustained for up to 3 years.
- IMPROVED FUNCTION
- QUALITY OF LIFE
5-YEAR STUDY ON NON-INVASIVE TREATMENT FOR HIP OSTEOARTHRITIS SHOWS SIGNIFICANT SURGERY AVOIDANCE
- SURGERY AVOIDANCE: Over 80% of the patients managed to avoid hip replacement surgery for at least three years
- SIGNIFICANT IMPROVEMENT IN THE QUALITY OF LIFE
- ENHANCED GAIT VELOCITY: 25% increase among the patients
SIGNIFICANT IMPROVEMENTS IN CHRONIC NONSPECIFIC LOW BACK PAIN
- PAIN: 57% reduction in pain on average
- Patients with knee OA walk faster, show improved step length and gait symmetry, indicating a healthier, less compensatory walking pattern
- Increased single limb support suggests better weight-bearing ability, an indication of better neuromuscular control
- Clinically, these changes promote greater independence, improved daily function, and enhanced quality of life while reducing the risk for surgery
OVER 50 PEER-REVIEWED CLINICAL STUDIES DOCUMENT THE POSITIVE IMPACT OF APOS®.
WE TURN RESEARCH AND INSIGHTS INTO NEW WAYS TO ADDRESS JOINT PAIN
AFTER SERVING MORE THAN 150,000 PATIENTS AND BASED ON 15 YEARS OF RESEARCH AND DEVELOPMENT, THE RESULTS OF APOS® SPEAK FOR THEMSELVES
Avg.
%
PAIN REDUCTION IN KNEE OA PATIENTS, AND 56% IN LOWER BACK1,2
Avg.
%
FUNCTION IMPROVEMENT IN KNEE OA PATIENTS1
%
OF TKR CANDIDATES AVOID SURGERY FOR UP TO 6 YEARS4
%
REDUCE THE USE OF PAIN MEDS, INCLUDING OPIOIDS
Reduction in pain meds and 85% reduction in opioid use in knee and lower back patients3
HEAR FIRSTHAND FROM LEADING PHYSICIANS
BEFORE AND AFTER APOS®
THE APOS® TREATMENT PROCESS
JUST THREE SIMPLE STEPS CAN HELP PATIENTS RECLAIM THEIR LIVES THAT JOINT PAIN TOOK AWAY
MEDICAL ADVISORS
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REFERENCES
1] Reichenbach A, Felson DT, Hincapi CA, Heldner S, Butikofer L, Lenz A, da Costa BR, Bonel HM, Jones RK, Hawker GA, Juni P. Effect of Biomechanical Footwear on Knee Pain in People With Knee Osteoarthritis. The BIOTOK Randomized Clinical Trial. JAMA 2020; 323(18):1802-1812.
2] Veeramachaneni R et al. Clinical outcomes of a new non-invasive biomechanical intervention for patients with chronic low back pain. A Randomized Clinical Trial. Aug;10(8):836-842. doi: 10.1016/j.pmrj.2018.02.005. Epub 2018 Feb 21.
3] Josh Mark, Shirley Shema-Shiratzky, Joel Sommer, Tim Nolan, Ganit Segal. Reduction in Healthcare Resource Utilization Following Treatment With a Home-Based Footworn Device in Patients With Knee Osteoarthritis: A Retrospective Claims Analysis. J Health Econ Outcomes Res. 2024 May 16; 11(1):134-140. doi: 10.36469/001c.117155.eCollection 2024. https://pubmed.ncbi.nlm.nih.gov/38765914/
4] Benn, R., Rawson, L., & Phillips, A. (2023). Utilising a non-surgical intervention in the knee osteoarthritis care pathway: A 6-year retrospective audit on NHS patients. Therapeutic Advances in Musculoskeletal Disease. https://doi.org/10.1177/1759720X231187190
